A teenage girl and her little brother must survive a wild 24 hours during which a mass hysteria of unknown origins causes parents to turn violently on their own kids.

Johnny Blaze, a man who made a deal with the Devil who called himself Mephistopheles at the time (now Roarke), is on the run trying to make sure no-one is harmed by his alter ego, The Ghost Rider. He is approached by a Monk named Moreau who tells him that he can help be him free of the Rider, but first, he needs Johnny's help to protect a boy, whom Roarke has plans for, to help him take human form.

Set in a future-world where humans can control other humans in mass-scale, multi-player online gaming environments, a star player from a game called "Slayers" looks to regain his independence while taking down the game's mastermind.

Chev Chelios survives a fall from the sky, sort of. He's in an unknown location, sedated, while various Chinese are harvesting his organs. His heart is gone, in an ice chest; a temporary in its place. Chev escapes, knowing only the name of the guy with the ice chest. He calls Doc Miles, an unlicensed cardiologist, who tells him there's only an hour's life in the artificial heart: keep it charged. Chev needs to find his own heart and get to Doc for a transplant. He starts his time-limited pursuit...

The hit-man Chev Chelios is poisoned by the criminal Verona and his friend and doctor Miles advises him that he must keep his adrenaline in an upper level to stay alive. Chev meets his girlfriend Eve and together he looks for Verona to kill him.